Chemical identity
Every value states its source: database, literature, or calculation. Calculated values are not presented as PubChem data.
| Compound class | Synthetic pentadecapeptide (15 amino acid residues) |
|---|---|
| Synonyms | BPC 157 · PL 14736 · Body Protection Compound 157 |
| Molecular formula | C62H98N16O22PubChem |
| Average molecular mass | 1419.5 г/мольPubChem |
| CAS | 137525-51-0PubChem |
| PubChem CID | 9941957PubChem |
| Chain length | 15 а.о.literature |
| Sequence | GEPPPGKPADDAGLVFormula and average mass were independently recomputed from the sequence shown and matched the PubChem record. |
Identity
BPC-157 (Body Protection Compound 157) is a synthetic peptide of 15 amino-acid residues. The literature describes it as a fragment related to a gastric-juice protein and uses the term "stable gastric pentadecapeptide", reflecting the molecule's stability in the gastric environment.
What preclinical studies show
A large body of rodent work covers models of gastrointestinal, tendon, ligament, muscle, and vascular injury, describing cytoprotective effects and accelerated healing. Proposed mechanisms include modulation of the nitric-oxide system and vessel recruitment.
A notable feature of this literature is that much of it originates from a single research group; independent replication elsewhere is limited. That matters when weighing the reliability of the findings.
Human data
No randomised controlled efficacy trials of BPC-157 in humans have been published, and no regulator has approved it as a medicine. Claims of proven clinical effects do not match the current literature.
Catalogue status
BPC-157 in the Moscow Peptides catalogue is a research material for laboratory use. It is not intended for human use. Batch documentation is published after its provenance is verified.
References
- Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract — Current Pharmaceutical Design (PMID 21548867), 2011.
- Novel Cytoprotective Mediator, Stable Gastric Pentadecapeptide BPC 157. Vascular Recruitment and Gastrointestinal Tract Healing — Current Pharmaceutical Design (PMID 29879879), 2018.
- Stable Gastric Pentadecapeptide BPC 157 and Wound Healing — Frontiers in Pharmacology, 12, 627533 (DOI 10.3389/fphar.2021.627533), 2021.
